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Joost J Oppenheim Selected Research

Type II Tumor Necrosis Factor Receptors

12/2021A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer.
1/2018Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer.
1/2017Targeting TNFR2, an immune checkpoint stimulator and oncoprotein, is a promising treatment for cancer.
10/2016Corrigendum: TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis.
1/2016TNFR2 expression by CD4 effector T cells is required to induce full-fledged experimental colitis.
6/2014Progranulin promotes tumour necrosis factor-induced proliferation of suppressive mouse CD4⁺ Foxp3⁺ regulatory T cells.
8/2011The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4(+) FoxP3(+) regulatory T cells.
7/2010Expression of costimulatory TNFR2 induces resistance of CD4+FoxP3- conventional T cells to suppression by CD4+FoxP3+ regulatory T cells.
4/2010Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+ regulatory T cells in human peripheral blood.
5/2008Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells.

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Joost J Oppenheim Research Topics

Disease

36Neoplasms (Cancer)
01/2022 - 01/2002
13Inflammation (Inflammations)
01/2022 - 02/2002
9Infections
01/2018 - 11/2002
8Breast Neoplasms (Breast Cancer)
01/2014 - 08/2002
6Neoplasm Metastasis (Metastasis)
01/2014 - 08/2002
6Autoimmune Diseases (Autoimmune Disease)
01/2013 - 01/2002
4Hyperalgesia
12/2014 - 07/2004
4Pain (Aches)
06/2011 - 08/2002
3Colitis
01/2020 - 01/2016
3Lewis Lung Carcinoma
07/2019 - 05/2008
3Carcinogenesis
11/2017 - 11/2004
3Melanoma (Melanoma, Malignant)
01/2015 - 09/2011
3Graft vs Host Disease (Graft-Versus-Host Disease)
02/2013 - 10/2005
3Systemic Scleroderma (Systemic Sclerosis)
11/2007 - 06/2005
3Myositis (Idiopathic Inflammatory Myopathies)
06/2005 - 01/2002
2Parkinson Disease (Parkinson's Disease)
11/2022 - 01/2017
2Colonic Neoplasms (Colon Cancer)
12/2021 - 01/2018
2Hepatocellular Carcinoma (Hepatoma)
07/2019 - 08/2017
2Hypersensitivity (Allergy)
11/2017 - 01/2013
2Necrosis
06/2014 - 08/2011
2Rheumatoid Arthritis
01/2010 - 10/2004
2Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
08/2006 - 06/2005
2Uveitis
06/2005 - 06/2005
2Lymphoma (Lymphomas)
06/2002 - 01/2002
1Communicable Diseases (Infectious Diseases)
01/2022
1Lung Neoplasms (Lung Cancer)
07/2019
1Wounds and Injuries (Trauma)
01/2018
1Ischemia
01/2018
1Experimental Melanoma
08/2017
1Ovarian Neoplasms (Ovarian Cancer)
01/2017
1Hyperplasia
01/2016
1Sarcoma (Soft Tissue Sarcoma)
12/2014
1Cancer Pain
12/2014
1Thymoma (Thymic Carcinoma)
11/2014
1Anthrax
08/2014

Drug/Important Bio-Agent (IBA)

16ChemokinesIBA
01/2013 - 01/2002
10Type II Tumor Necrosis Factor ReceptorsIBA
12/2021 - 05/2008
9AlarminsIBA
01/2018 - 01/2007
8Chemotactic FactorsIBA
01/2022 - 02/2002
8HMGN1 Protein (HMGN1)IBA
12/2021 - 11/2014
8Peptides (Polypeptides)IBA
10/2021 - 05/2005
8Proteins (Proteins, Gene)FDA Link
01/2017 - 11/2004
7AntigensIBA
10/2017 - 01/2002
7Chemokine ReceptorsIBA
12/2005 - 08/2002
6LigandsIBA
01/2018 - 05/2002
5CytokinesIBA
01/2018 - 05/2002
4AntibodiesIBA
01/2022 - 08/2002
4DefensinsIBA
07/2013 - 01/2002
4AutoantigensIBA
06/2005 - 01/2002
3Cyclophosphamide (Cytoxan)FDA LinkGeneric
10/2017 - 01/2014
3VaccinesIBA
10/2017 - 06/2002
3Opioid Analgesics (Opioids)IBA
12/2014 - 08/2002
3Type I DNA Topoisomerases (Topoisomerase I)IBA
11/2007 - 05/2002
3Epidermal Growth Factor (EGF)IBA
03/2007 - 08/2003
3AutoantibodiesIBA
06/2005 - 01/2002
3Transfer RNA (tRNA)IBA
06/2005 - 01/2002
2alpha-SynucleinIBA
11/2022 - 01/2017
2Interleukin-8 (Interleukin 8)IBA
01/2022 - 08/2002
2Messenger RNA (mRNA)IBA
01/2022 - 01/2013
2Immunologic Adjuvants (Immunologic Adjuvant)IBA
10/2021 - 06/2002
2cryptotanshinoneIBA
07/2019 - 07/2019
2OligodeoxyribonucleotidesIBA
01/2018 - 06/2011
2Neoplasm Antigens (Tumor Antigens)IBA
08/2017 - 01/2002
2DNA (Deoxyribonucleic Acid)IBA
01/2015 - 07/2013
2Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
06/2014 - 12/2011
2trioctyl phosphine oxide (TOPO)IBA
11/2007 - 06/2006
2LipidsIBA
03/2007 - 10/2005
2Retinaldehyde (Retinal)IBA
06/2005 - 06/2005
2asparaginyl-tRNA synthetaseIBA
06/2005 - 09/2002
2Histidine-tRNA LigaseIBA
06/2005 - 09/2002
2interstitial retinol-binding proteinIBA
06/2005 - 06/2005
2Chemokine CXCL12IBA
02/2005 - 08/2003
2G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
11/2003 - 08/2002
2beta-DefensinsIBA
11/2002 - 06/2002
2Ligases (Synthetase)IBA
09/2002 - 01/2002
1Immune Checkpoint InhibitorsIBA
01/2022
1Indicators and Reagents (Reagents)IBA
12/2021
1Small Cytoplasmic RNAIBA
10/2021
1EnzymesIBA
01/2020
1tetrandrineIBA
01/2020
1Cyclin B1IBA
07/2019
1CPG-oligonucleotideIBA
01/2018
1InterferonsIBA
01/2018
1Toll-Like Receptor 9IBA
01/2018
1Oncogene Proteins (Oncogene Protein)IBA
01/2017
1Interleukin-22 (IL-22)IBA
01/2016
1GelsIBA
01/2015
1kushenIBA
12/2014
1Phosphotransferases (Kinase)IBA
12/2014
1Capsaicin (Zostrix)FDA Link
12/2014
1OvalbuminIBA
11/2014
1A-Form DNA (A-DNA)IBA
11/2014
1Capsules (Microcapsules)IBA
08/2014
1ProgranulinsIBA
06/2014
1Antineoplastic Agents (Antineoplastics)IBA
01/2014

Therapy/Procedure

8Therapeutics
01/2022 - 08/2006
4Immunotherapy
12/2021 - 01/2018
2Injections
08/2017 - 06/2004
1Drug Therapy (Chemotherapy)
12/2014
1Chinese Traditional Medicine (Traditional Chinese Medicine)
12/2014